Dry Ice versus Liquid Nitrogen

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The page below is a sample from the LabCE course Dry Ice and Liquid Nitrogen Safety. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Dry Ice versus Liquid Nitrogen

Table 1. Summary of Dry Ice versus Liquid Nitrogen.

Dry IceLiquid Nitrogen
Chemical formulaCO2N2 or LN2
StateSolidLiquid
AppearanceWhite, opaqueColorless, clear
SmellOdorlessOdorless
Special propertySublimates directly from solid to gasBoils at -196°C (-320°F)
Laboratory usesSample preservation and transportSample preservation and transport
PPE requirementsCryogenic gloves, lab coat, face shield or safety glasses/goggles, long pants, close-toed shoes Cryogenic gloves, lab coat, face shield or safety glasses/goggles, long pants, close-toed shoes
Storage containerInsulated, non-airtight container; typically foam or plastic with foam insulationDewar flask
Code of federal regulationsCFR Title 49CFR Title 49
DisposalAllow to sublimate in a well-ventilated areaAllow to evaporate in a well-ventilated area
First aidTreat frostbite with lukewarm water for 15 minutes; move to fresh air for inhalation issues; seek medical attention for frostbite, eye exposure, or difficulty breathingTreat frostbite with lukewarm water for 15 minutes; move to fresh air for inhalation issues; seek medical attention for frostbite, eye exposure, or difficulty breathing