Prevotella

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The page below is a sample from the LabCE course Medically Important Anaerobes. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Prevotella

Significant Prevotella species include:
  • P. bivia
  • P. disiens
  • P. intermedia
  • P. menaninogenica
Things to remember:
  • Normally associated with oral, vaginal, and intestinal flora, but may cause infections associated with abscesses.
  • Aspiration pneumonia, lung abscesses, periodontal abscesses, and abscesses in many other locations (i.e., brain, sinus) may result.
  • P. melaninogenica is one of the most prevalent anaerobes in infected bite lesions.11
11. Carroll KC, Pfaller MA, Karlowsky JA, Landry ML, McAdam AJ, Patel R, & Pritt, BS, eds. Manual of Clinical Microbiology. 13th edition. ASM Press. 2023.
Figure 30. Centers for Disease Control and Prevention. (1965). Gram stain of Prevotella melaninogenica bacteria, formerly known as Bacteroides melaninogenica, which had been grown in thioglycollate medium for a 72-hour time period. [Image]. https://phil.cdc.gov/Details.aspx?pid=15232.
Figure 31. Centers for Disease Control and Prevention. (1977). Pigmented colonies of Prevotella melaninogenica, formerly known as Bacteroides melaninogenicus bacteria. [Image]. https://phil.cdc.gov/Details.aspx?pid=15241.

Figure 30. Gram stain of Prevotella melaninogenica bacteria,
isolated from a broth culture after 72-hour incubation
Figure 31. Selective blood agar media containing kanamycin.
Growth after 5 days gave rise to pigmented colonies of Prevotella melaninogenica.