Lymphocytes vs. Monocytes

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The page below is a sample from the LabCE course Body Fluid Differential Tutorial. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Lymphocytes vs. Monocytes

The image is a microscopic field from a CSF cytospin. The red arrow points to a monocyte, and the blue arrow points to a lymphocyte. The lymphocytes in this field have a more regular cytoplasmic border without the cytoplasmic blebbing and pseudopods that are present in monocytes. Monocytic cells seen in body fluids have variable morphology as they have the ability to transform into phagocytic macrophages.