Epigenetic Biomarker Testing

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The page below is a sample from the LabCE course Epigenetics: Diagnostic Methods in the Clinical Laboratory. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Epigenetics: Diagnostic Methods in the Clinical Laboratory (online CE course)
Epigenetic Biomarker Testing

Epigenetic biomarker applications in the clinical laboratory are becoming regularly present via the following methodologies:
  • RT-qPCR System
  • Gene-specific DNA Methylation
  • miRNA measurement
  • Histone post-translational modifications (PTM) studies
  • Next-Generation Sequencing (NGS)
  • Mass Spectrometry
Development of new technologies targeting epigenetic markers has been used in:
  • In-house laboratory developed tests (LDTs)
  • In vitro diagnostics (IVD)
  • In vitro diagnostics manufacturers
  • Kits for the detection of epigenetic biomarkers