Case Study 2: Phenotypically Similar Cells

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The page below is a sample from the LabCE course A Comprehensive Overview of "HTLA" and "HTLA-Like" Antibodies. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Case Study 2: Phenotypically Similar Cells

Noticing the panreactive but variable reactivity, the reference laboratory decided to perform a full serological phenotype on the patient and run several phenotypically similar cells to determine if the reactivity was caused by a combination of common red cell antibodies, or by an antibody to a high-prevalence antigen.
Patient's ABO/Rh and serological phenotype: O-; C- E- c+ e+; K- k+; Fy(a-b+); (Jka+b+); M+ N+; S- s+
Rh-HrKellDuffyKiddLewisMNSsP1LutheranXg
Cell NumberDCcEeVCwKkKpaKpbJsaJsbFyaFybJkaJkbLeaLebMNSsP1LuaLubXgaAHG (PEG)
100+0+000+0+0+0++++0++0++0++1+
200+0+000+0+++00+0000+0++0++w+
300+0+000+0+0+0+0+0++00++0+01+
Note that the highlighted cells are the antigens which match the patient.