Overview of Bilirubin

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The page below is a sample from the LabCE course Chemical Screening of Urine by Reagent Strip. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Overview of Bilirubin

Bilirubin, a product of hemoglobin catabolism, is characterized by its distinctive yellow pigment. Only conjugated bilirubin is excreted in urine. If bilirubin is elevated and is conjugated, it will be detected by the urine reagent strip.
A detectable amount of bilirubin in urine is always abnormal.
The kidneys cannot excrete unconjugated bilirubin because it is bound to albumin and is water insoluble.