Red Cell Disorders: Peripheral Blood Clues to Nonneoplastic Conditions (Online CE Course)

(based on 357 customer ratings)

Authors: C. William Reiquam, MD; Elmer W. Koneman, MD
Reviewer: Rory Huschka, M.Ed., MT(ASCP)

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This collection of informative case studies covers many current topics in red cell disorders. Topics include macrocytosis, intracellular RBC inclusions, echinocytes and acanthocytes, schistocytes, ovalocytes, and rouleaux. Numerous high-quality photomicrographs and real-life situations help ensure learning and retaining needed information.

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Approved through 5/31/2024
Approved through 5/31/2024

Objectives

  • Review normal and abnormal red blood cell morphologies.
  • Recall the criteria for performing and reporting peripheral blood smear reviews.
  • Demonstrate ability to evaluate red blood cell size, shape, and staining characteristics.
  • Correlate observations of key red blood cell abnormalities on peripheral smears with associated clinical conditions.
  • Recognize, via case studies, peripheral smear evaluations for red blood cell morphology and their clinical implications.

Customer Ratings

(based on 357 customer ratings)

Course Outline

Click on the links below to preview selected pages from this course.
  • Introduction to Red Blood Cell Morphology
  • Abnormal Red Blood Cell Morphology Review
  • Case Studies in Red Blood Cell Nonneoplastic Conditions
      • Introduction to Case Studies
    • Hemolytic Conditions with Spherocytosis
      • Case Study OneA 12-year-old child presents with jaundice and scleral icterus. The image to the right captures a representative section of the peripher...
      • Case Study One (continued)Which hematologic condition could be associated with the findings shown in this image?
      • Case Study Two A known case of hemolytic disease of the fetus and newborn (HDFN) is presented in the image on the right. Many different cellular morph...
      • Case Study ThreeA 49-year-old patient with pneumonia was treated with high-dose intravenous penicillin. The patient became jaundiced with yellow scler...
    • Macrocytosis-Associated Conditions
      • Case Study FourA complete blood count (CBC) was ordered for a patient recently admitted to the emergency department. The MCV on the count was 115 femt...
      • Case Study FiveA patient has an elevated MCV on the automated CBC and a peripheral blood smear is reviewed. A representative field is shown on the rig...
    • Intracellular RBC Inclusions
      • Case Study SixA 25-year-old asplenic patient with disseminated lymphoma is admitted to the hospital. A CBC is ordered, and a peripheral blood smear is...
      • Case Study SevenA toddler is being treated for lead poisoning. You observe the inclusions indicated by the arrows in many RBCs on the peripheral blood...
      • Case Study EightA 66-year-old patient has been diagnosed with sideroblastic anemia. The inclusions indicated by the arrows in the image were seen in m...
      • Case Study NineA 10-year-old child came to a physician's attention because of recent jaundice and icteric sclerae after taking the medication Primaqui...
    • Dimorphic Red Blood Cell Populations
      • A blood smear represented by the photograph was submitted for hematologic review. Based on the erythrocyte morphology and the accompanying histogram, ...
    • Target cells and Sickle Cells
      • Hemoglobin E (HbE) and HbE/Beta Thalassemia
      • Case Study A five-month-old Asian child is brought to the pediatrician by her mother who is concerned because the child is not eating well. Upon exami...
      • A CBC and reticulocyte count are ordered on a 10-year-old African-American male who was brought to the emergency department with rapid, shallow breath...
      • Sickle cells along with target cells, as shown in this image, confirm a diagnosis of sickle cell disease (HbSS).
    • Schistocytes, Bite Cells, and Teardrop Cells
      • Case Study A patient is diagnosed with disseminated intravascular coagulation (DIC) based on clinical findings and laboratory results that include dec...
      • The top image on the right represents a Wright-stained microscopic field from a peripheral blood smear. The bottom image represents a microscopic fiel...
      • The cells indicated by the arrows provide a clue to the diagnosis of chronic idiopathic myelofibrosis (primary myelofibrosis). What is the identity of...
      • A 5-year-old girl was brought to the emergency department with bloody diarrhea and severe abdominal pain. A complete blood count produced these result...
    • Ovalocytes, Elliptocytes and Stomatocytes
      • Ovalocytes/Elliptocytes
      • Stomatocytes
      • Case StudyA 13-year-old healthy male presents to his physician for a sports physical. A complete blood count (CBC) is ordered. The automated count tri...
    • Multiple Erythrocyte Abnormalities
      • Case Study
      • Case Study, continued: Splenectomy Morphologies
      • Case Study, continued: Poikylocytosis and Basophilic Stippling
      • This slide is from a 28-year-old female who received a kidney transplant, which was preceded by a splenectomy six months prior to the kidney transplan...
  • References
      • References

Additional Information

Level of Instruction: Intermediate

Intended Audience: Clinical laboratory science students, and medical technologists and technicians seeking review, cross training, or continuing education opportunities. It is also appropriate for medical students and pathology residents.
 
Author information: C. William Reiquam, MD (1923-2015) was a clinical professor of pathology in the School of Medicine, University of Colorado. One of his areas of expertise was hematology.

Author information: Until his recent passing, Elmer W.Koneman M.D. was Professor Emeritus, Department of Pathology, University of Colorado School of Medicine. Dr. Koneman was a Board Certified Pathologist, former full Professor of Pathology University of Colorado School of Medicine. He was the author of numerous journal articles and books.

Reviewer information: Rory Huschka, M.Ed., MT(ASCP) is a Program Director at MediaLab Inc. He holds a BS degree from North Dakota State University in Medical Technology and an MS degree in Educational Leadership. He is a former Program Director for both MLT and MLS programs. Rory continues to teach as an adjunct professor for various colleges and universities. 

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 176 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
Need multiple seats for your university or lab? Get a quote
table acantocyte


table agglutination


table burr cells


table macrocytes


table microcytes


table target cells


table sickle cells


table spherocytes