Course Outline
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- Introduction to Cystic Fibrosis
- The History of CF
- History of CF and Diagnostic Testing
- Pathophysiology of CF
- Pathophysiology of CF
- Mutations of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)
- CF is due to a defect in a protein which functions as a(n):
- Clinical Presentation
- Overview of Clinical Characteristics
- Pulmonary Disease
- Pancreatic Disease
- Sweat Gland Involvement
- Gastrointestinal and Liver Disease
- Reproductive System
- Which of the following pathogens is not typically associated with CF pulmonary disease?
- Which of the following statements concerning the sweat of patients with CF is true?
- Laboratory Diagnosis of CF
- Sweat Testing
- Sweat Testing
- Sweat Stimulation
- Sweat Collection
- Collecting An Adequate Sweat Sample
- Quantitative Sweat Analysis
- Screening Tests for Sweat
- Reference Intervals for Sweat Chloride
- Reference Intervals for Sweat Conductivity
- Quality Assurance for Sweat Testing
- CF is the only disorder that will result in increased sweat chloride concentrations.
- When performing sweat testing for CF diagnosis, how long is sweat stimulated by iontophoresis and how long is it collected?
- Treatment
- Treatment
- Treating the Symptoms
- Treating the Protein Defect
- Gene Replacement
- Which of the following statements is true concerning medications that treat the protein defect in CF?
- Summary
- References
Additional Information
Level of instruction: Intermediate
Intended Audience: This course is designed for medical laboratory scientists, medical technologists, and medical laboratory technicians. This course is also appropriate for medical laboratory science students and pathology residents.
Author information: Vicky LeGrys, DA, MT(ASCP) is a professor in the Division of Clinical Laboratory Science in the School of Medicine at the University of North Carolina Chapel Hill where she is responsible for the lecture and laboratory courses in Biochemistry, Clinical Chemistry, and Quality Assurance. She holds a Doctorate of Arts and a Master of Science in Medical Technology from the Catholic University of America, Washington DC with a major in Clinical Chemistry.
Reviewer information: DeRhonda Crawford, MT(ASCP) is the chemistry supervisor at Gwinnett Medical Center in Lawrenceville, Georgia and the technical supervisor for the Gwinnett Medical Center in Duluth, Georgia. She holds a BS in Medical Technology from the Medical College of Georgia.
