Course Outline
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- Introduction
- Variations in Morphology
- Importance of Recognition
- Match the following:
- Nuclear Variations
- Cytoplasmic Variations
- Döhle Bodies
- Döhle Bodies, continued
- Toxic Granulation
- Toxic Granulation and Vacuolation
- Cytoplasmic Vacuolation
- Neutrophil with Normal Granulation
- Toxic granulation is seen most frequently in:
- Auer Rods
- Auer Rods, continued
- Which of the following inclusions may be seen in the cytoplasm of myeloblasts and promyelocytes?
- Auer rods are significant when they are seen in the cytoplasm of blast cells because they are diagnostic for:
- Chédiak-Higashi Syndrome
- Albinism and Chédiak-Higashi Syndrome
- Chédiak-Higashi Syndrome vs. Toxic Granulation
- Chediak-Higashi Syndrome Inclusions
- Chediak-Higashi Syndrome is characterized by which of the following?
- May-Hegglin Anomaly
- Alder-Reilly Anomaly
- Alder-Reilly Anomaly, continued
- Alder-Reilly anomaly inclusions may be found in which of the following white blood cell types?
- Which of the following inclusions has a similar appearance on a Wright's stained smear to a Döhle body?
- The inclusions that are frequently seen on the same peripheral blood smear with toxic granulation include: (Choose ALL that apply)
- What type of inclusions are present in the cell that is indicated by the arrow?
- The cell in this image is typical of other neutrophils on this peripheral blood smear from a patient with sepsis. Which morphologic term describes the...
- Summary
- References
Additional Information
Level of instruction: Intermediate
Intended Audience: clinical laboratory science students, medical technologists, and medical laboratory technicians seeking review or continuing education. It is also appropriate for medical students, pathology residents, and pathologists.
Course Description: This course covers morphologic variations observed in granulocytes, including nuclear and cytoplasmic variations.
Authors: by Marjorie A. Spahn, MT (ASCP) and Barbara Minderman, MT (ASCP).
Reviewer: Rory Huschka, M.Ed., MT(ASCP), has over 25 years of combined experience as a medical technologist, technical supervisor, professor, and manager. He is a former Director of Medical Laboratory Science and Medical Laboratory Technician Programs. He is currently a Program Director at MediaLab, Inc. Rory holds a BS degree in Medical Technology from North Dakota State University and a Masters in Educational Leadership.
Reviewer: Patrick Tracy, MA, MLS(ASCP), has been an MLT program director since 2012. His teaching experience has been in student labs, both face to face and online. His contribution to medical-laboratory education is most pronounced by his microbiology, blood bank and chemistry YouTube channel.