Prostate Biopsies (Online CE Course)

Author: Kristen Meyer, BS, HTL(ASCP), QIHC(ASCP)
Reviewer: Kara Goplerud, BS

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Approved through 5/31/2028
Approved through 5/31/2028

Objectives

  • Identify microscopic structures of the prostate.
  • Define the most common conditions affecting the prostate.
  • Explain proper handling of prostate biopsies in the histology laboratory.
  • Describe the use of special stains, IHC, and molecular methods for the diagnosis of prostate cancer.

Course Outline

Click on the links below to preview selected pages from this course.
  • Foundations of Prostate Anatomy and Histology
      • Introduction
      • Anatomy of the Prostate
      • Zones of the Prostate
      • Histology of the Prostate
      • What is the primary function of prostate basal cells?
      • What is calcified secretory fluid trapped in luminal spaces called?
  • Prostate Cancer Screening and Early Detection
      • Screening for Prostate Cancer: Blood Tests
      • Screening for Prostate Cancer: Visual Exams
      • What are some things that can lower blood PSA levels and produce false negative results?
      • Which is a type of visual exam used to screen for prostate cancer?
  • Benign and Pre-Malignant Prostate Conditions
      • Prostatitis
      • Benign Prostatic Hyperplasia
      • Prostatic Intraepithelial Neoplasia
      • Which cellular architecture of HGPIN presents with small clusters of cells within the lumen?
      • Transurethral resection (TURP) of the prostate is a surgical procedure commonly used to treat which condition?
  • Prostate Cancer Overview
      • Prostate Cancer
      • Which is the most common type of prostate cancer?
      • High grade cancer has a Gleason score of:
  • Procedures and Collection Methods
  • Histologic Testing
  • Summary
      • Conclusion
  • References

Additional Information

Level of Instruction: Basic
Intended Audience: Histotechnologists, histotechnicians, pathologists' assistants, laboratory supervisors, and laboratory managers. This course is also appropriate for HTL and HT students, cytologists, and pathology residents.
Author Information: Kristen Meyer, BS, HTL(ASCP), QIHC(ASCP), is the Manager of Anatomic Pathology Services for Kaiser Permanente in Portland, OR. She graduated from Tulane University with a Bachelor of Science degree in Biology. Upon graduation, she began working in a hospital as a clinical lab assistant, and from there became interested in Histotechnology after observing gross dissections of specimens in the Pathology department. Since then, she has worked in the Histopathology field for over 20 years in various roles, including Histotechnologist, Technical Specialist, Supervisor, and Manager. 
The author has no conflict of interest to disclose.
Reviewer Information: Kara Goplerud, BS, is the Lead Histology Technician at Kaiser Permanente in Portland, Oregon. She earned a Bachelor of Science in Biology with a Pre-Medicine focus from Portland State University. During her undergraduate studies, she developed a strong interest in pathology while performing necropsies on cetaceans. With over a decade of experience in the field, Kara now focuses on training new histology technicians and driving process improvement initiatives.

Figure 2. Anatomical zones of the prostate


Figure 9. Types of BPH, stained with H&E


Figure 10. High-grade PIN patterns