Course Outline
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- Introduction to Leukemia
- Introduction to Leukemia Case Studies: WHO Classification 2022
- Introduction to Leukemia Case Studies
- Hematopoiesis Theory
- All of the following cells originate from the myeloid cell line except:
- Definition and Pathophysiology of Leukemia
- What Causes Leukemia?
- Predominant Types of Leukemia
- Acute and Chronic Leukemia
- Chronic Leukemias
- Acute Leukemias: Myeloid Cell Line
- Select all of the following ways acute leukemias are classified based on the WHO 2022 classification system.
- Acute Leukemias: Lymphoid Cell Line
- Which classification of leukemia is described as a rapid proliferation of immature cells that crowd out the bone marrow with the presence of >20% b...
- Laboratory Tests to Differentiate Leukemias
- Case 1: 12-Year-Old Child with Fever, Bruising, and Chest Pain
- Clinical Presentation
- Initial Laboratory and X-Ray Findings
- Interpretation of Laboratory and X-Ray Results
- Additional Testing: Cytochemical Staining
- Additional Testing: Immunophenotyping
- Based on the results of the cytochemical stains from the patient, which were MPO negative and block positive with PAS, what type of cells are present ...
- Which CD marker is a T cell marker that can be present in T-cell ALL?
- Diagnosis and Discussion
- Case 2: 60-Year-Old with Marked Leukocytosis, Basophilia, and Eosinophilia
- Clinical Presentation
- Initial Laboratory Findings
- Interpretation of Laboratory Results
- Additional Laboratory Testing
- Additional Testing: LAP Stain
- Additional Testing: Flow Cytometry and FISH Studies
- Which of the following stains could help differentiate the disorder based on the left shift and the high WBC count present?
- What cytogenetic abnormality must be present to confirm the diagnosis of CML?
- Diagnosis and Discussion
- Case 3: 21-Year-Old with a History of Gingival Bleeding
- Case 4: 66-Year-Old with a 3-Month History of Persistent Fatigue
- References
Additional Information
Level of Instruction: Intermediate
Intended Audience: Medical laboratory scientists, medical laboratory technicians, laboratory supervisors, and laboratory managers. This course is also appropriate for MLS and MLT students and pathology residents.
Author Information: Autumn Vela, MHA, MLS(ASCP)
CMSH
CM, is a Clinical Assistant Professor in the Medical Laboratory Science (MLS) program at Texas State University in San Marcos, TX. She teaches a variety of courses within the program, with a particular passion for Hematology. Autumn earned her Bachelor of Science in Medical Laboratory Science from George Washington University and her Master of Healthcare Administration from Texas Tech University. She is certified by the ASCP as a Medical Laboratory Scientist and as a Specialist in Hematology. With over 12 years of experience in the field, she has held multiple roles, including serving as a multi-site laboratory manager, before transitioning to an academic role.
The author has no conflict of interest to disclose.
Reviewer Information: Valerie F. Jalicke, MS, MLS(ASCP)CMPBTCM, received her Bachelor of Science and Master of Science in Bioscience Technologies from Thomas Jefferson University in Philadelphia, PA. She currently serves as Program Director and Clinical Assistant Professor in the Medical Laboratory Science program at Thomas Jefferson University. She has over 30 years of experience as a medical laboratory scientist with a heavy focus on hematology, clinical chemistry, and urinalysis and body fluids.
