Body Fluid Differential Tutorial (Online CE Course)

(based on 1,506 customer ratings)

Author: MaryBeth Helfrich, MT(ASCP)
Reviewer: Paul Fekete, MD, FCAP

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If you have forgotten the art of differentiating choroid plexus cells from ependymal cells or viral lymphocytes from fluid monocytes, you are in luck! This course provides a thorough morphologic identification of over 40 cell types and disease states to recharge your memory. The course features over 100 crystal clear, perfectly stained body fluid images to illustrate both basic and advanced cellular morphology - perfect for a comprehensive, detailed review which can help refresh any technologist, both in or out of the hematology laboratory. The course is P.A.C.E. approved for 2 full credit hours to help reach your continuing education credit requirements. Enjoy learning and/or reviewing the key identification characteristics of body fluid cells in a user-friendly and fun format. Enroll today!

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Approved through 4/30/2024
Approved through 4/30/2024

Objectives

  • Compare and contrast the morphology of cells found in normal cerebrospinal fluid (CSF), normal pleural fluid, normal peritoneal fluid, and normal synovial fluid.
  • Identify the morphology of cells found in bronchoalveolar lavage (BAL).
  • Distinguish abnormal/reactive/infected cell morphology in fluids.
  • Recognize malignant cell morphology in body fluids.
  • Discuss appropriate scenarios for hematology/pathology review.

Customer Ratings

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Course Outline

Click on the links below to preview selected pages from this course.
  • Cytocentrifugation Morphology
      • Cytocentrifugation of Body Fluid Samples
  • Cell Types Common To Most Types of Body Fluids
    • Neutrophils
      • Neutrophils
      • Neutrophils, continued
      • Eosinophils vs. Neutrophils
      • Nucleated blood cells will always have the same appearance on a cytocentrifuged smear as they do on a peripheral blood smear.
    • Lymphocytes, Atypical Lymphs, Plasma Cells
    • Monocytes and Macrophages
      • Monocytes
      • Monocytes vs Lymphocytes
      • Monocytes and Macrophages
      • Macrophages
      • Phagocytosis
      • Hemosiderin
      • Histiocytes
      • (True/False) Macrophages are the phagocytes that originate from lymphocytes.
      • Match each cell type listed in the drop down box to the letter that corresponds to its identification in the image on the right.
  • Cells Found in Cerebrospinal Fluid
    • Cerebrospinal Fluid: Non-Blood Cells
    • Cerebrospinal Fluid: Bone Marrow Contamination
      • Bone Marrow Contamination in CSF
      • What is the identification of this cellular clump found in CSF? Note the presence of many similar-appearing nuclei without distinct lines of demarcati...
  • Cells Found in Pleural and Peritoneal Fluids
  • Cells Found in Synovial Fluids
  • Cells Found in Bronchoalveolar Lavages
    • Bronchial Lining Cells
      • Bronchial Lining Cells
      • Bronchial Lining Cells, continued
      • Match the following cell types to the body fluids in which they may be seen when the fluid is observed on a cytocentrifuged preparation.
  • Infectious Organisms in Body Fluids
  • Malignant Fluids with Leukemia and Lymphoma.
    • Lymphoid Leukemia / Lymphomas
      • Acute Lymphoblastic Leukemia (ALL): L1 Morphology
      • Central Nervous System (CNS) Relapse: L2 Acute Lymphoblastic Leukemia (ALL)
      • Burkitt Lymphoma
      • Non-Hodgkin Lymphoma
      • Anaplastic Large Cell Lymphoma (ALCL)
    • Myeloid Leukemias
      • Acute Myeloid Leukemia (AML)
      • Acute Myeloid Leukemia (AML), continued
      • Acute Monoblastic Leukemia (AMoL)
      • Prominent vacuolation involving the cytoplasm of abnormal lymphoblast-like cells seen in a body fluid preparation is a distinctive feature of Burkitt ...
  • Malignant Fluids with Metastatic Tumor
  • References
      • References

Additional Information

Level of Instruction: Intermediate
Intended Audience: This course is intended for laboratory professionals who have experience with peripheral blood morphology and basic experience with body fluid differential analysis.  This tutorial will provide a review of normal and abnormal body fluid morphology utilizing Wright-Giemsa stained cytospin preparations from cerebrospinal fluid (CSF), pleural, peritoneal, and synovial fluids, as well as bronchial alveolar lavage (BAL) samples.
Author Information: Marybeth Helfrich, MT(ASCP) is currently a Laboratory Technologist Specialist for the Hematology/Oncology Laboratory at Children's Hospital of Philadelphia. She received her BS, MT from Temple University in Philadelphia and has nearly 40 years of experience in both adult and pediatric hematology and oncology settings. She is a regular presenter for ASCLS-PA, has been a presenter for ASCP (local and national), and the Texas Teleconference network. She is responsible for hematology morphology instruction and training for medical technologists and fellows. She is also a regular developer of morphology tutorials for in-house continuing education activities.
Reviewer Information: Paul Fekete, MD, FCAP is the President and CEO of MediaLab, Inc. He received his MD from Ohio State University and completed his clinical pathology residency at Emory University in Atlanta. He has served as an Assistant Professor of Pathology at Emory, the Director of Laboratories for Gwinnett Medical Center in Lawrenceville, GA., and President of Gwinnett Pathology Associates.  Dr. Fekete is a member of Alpha Omega Alpha Honor Medical Society and a Fellow of the College of American Pathologists.

Keywords

These are the most common topics and keywords covered in Body Fluid Differential Tutorial:

lymphoid microbiology effusion clusters metastatic softer iron fungal lymphoma bi-nucleate pericardial hematology granulation leukemia choroid infection nuclearcytoplasmic white blood cells vacuolated photos saline proportions pneumonia chemotherapy ventricles acute cerebrospinal shaggy reactive cerebrospinal fluid mononuclear cells monocyte diplococci lavage textures respiratory clumps hyphae serous arthritis peripheral blood smears nervous adenocarcinoma neutrophils multinucleated artifact cilia blood primitive immature hemorrhage clinical brain cytoplasm wright plasmacytoid meningitis granules diagnosis bacterial tumor demarcation mesothelium membranes morphology lavages cytoplasmic samples identification neural peripheral blood smear pleural burkitt burkitts nuclei nucleus circulating malignant body mycobacteria macrophages multinucleate hospital organisms infectious numbers nerve toxoplasmosis lymphocyte histocytes red blood cells synovial sterile depicts fluids pathology intracellular rectangular chromatin nucleoli alveolar cellular vacuoles irregularity peritoneal spinal non-granular hospitals cavities wbcs cytospin technique mesothelial cells protocols trauma hemosiderin melanoma rbcs differential cytospin neuroectodermal lymphoblastic bals cavity macrophage lymphoblasts albicans tumors cytospins disease cells mesothelial generous rhabdomyosarcoma monocytes basophilic infections translocation fused laboratorians bronchial histiocytes lymphocytes myeloid bowel lymph cytospin preparation mesothelial cell cytospin preparations candida vacuolation nuclear abnormal effusions laboratory leukemic differentials histiocyte neuroblastoma bone marrow ependymal bacteria
How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 180 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
Need multiple seats for your university or lab? Get a quote
anaplastic large cell 2 sml


csf 10 sml


csf atyp lymph vs mono sml2


corrected normal csf 1 sml2


lymhoblasts sml


synovial clump sml


trauma pert lavage sml2


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