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- Course Information
- Review of Hemostasis Physiology
- Basic Definitions and Components
- Primary Coagulation
- Primary Coagulation
- Thromboxane A2 and ADP are exposed as a result of damage to a blood vessel wall, resulting in platelet adhesion and activation.
- Platelet Production
- Secondary Coagulation
- Coagulation Inhibition and Fibrinolysis
- Overview of Coagulation Inhibition and Fibrinolysis
- Three Natural Inhibitors of Coagulation
- Which of the following is a natural inhibitor of coagulation?
- Antiplatelet and Anticoagulant Pharmacology
- Overview of Hemostasis and Thrombosis Pharmacology
- Antiplatelet Medications
- Alteplase and Streptokinase
- In a patient experiencing a stroke, tPA can be used for up to ____ hours after the onset of symptoms.
- Coagulation Agonists
- Overview of Coagulation Agonists
- Coagulation Factors and Desmopressin
- Clinical Correlation: Hemophilia A and B
- Clinical Correlation: von Willebrand Disease (vWD)
- Vitamin K
- Identify if the coagulation factors listed are vitamin K-dependent or non vitamin K-dependent.
Level of Instruction: Intermediate
Intended Audience: Medical laboratory scientists, medical technologists, and technicians. This course is also appropriate for medical laboratory science students, pathology residents, and other healthcare personnel who are responsible for prescribing and administering antiplatelet and anticoagulant medications.
Author Information: Kyle D. Mills, DO, MLS(ASCP)SH, completed his professional medical education at the University of Pikeville - Kentucky College of Osteopathic Medicine in Pikeville, Kentucky, in 2018. He is currently pursuing residency in internal medicine at the University of Louisville in Louisville, Kentucky. Dr. Mills also holds a Bachelor of Health Science in Clinical Laboratory Sciences degree from the University of Kentucky and is an American Society for Clinical Pathology (ASCP) certified Medical Laboratory Scientist (MLS) and Specialist in Hematology (SH). Before attending medical school, Dr. Mills worked on the laboratory bench as a generalist and led a medical laboratory technician program.
Reviewer Information: Katie Blain, PharmD, MPH is a pharmacist with the Appalachian Regional Healthcare health system in Eastern Kentucky and Southern West Virginia. Dr. Blain currently serves as the Kentucky Pharmacists Association (KPhA) New Practitioner Committee Chair. She completed an American Society of Health System Pharmacy (ASHP) accredited community pharmacy residency program with Sullivan University College of Pharmacy and Walgreens Co. in Louisville, Kentucky. Dr. Blain received her Doctor of Pharmacy and Master of Public Health degrees from the University of Kentucky.
Course Description: This course will reintroduce older pharmacologic therapies, as well as introduce new therapies. The course will begin with a review of hemostasis physiology, continue with an overview of antiplatelet and anticoagulant pharmacology as it stands today, and end with a review of coagulation assays that may be seen in the clinical laboratory.