Clinical Presentation: Scrapie

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The page below is a sample from the LabCE course Overview of Prion Diseases. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Clinical Presentation: Scrapie

Clinical manifestations are relatively mild early in the infection. As the disease progresses, neurological signs develop along with weight loss, lethargy, loss of muscle coordination, and eventually death. As stated previously, sheep may scratch excessively, showing patches of wool loss and skin lesions. There is no known treatment.