The second technique for isolating fetal DNA from maternal DNA is targeted DNA analysis.
This technique involves selective sequencing of relevant chromosomes. In targeted DNA analysis, specific cfDNA fragments from maternal blood are used for selective sequencing. Digital analysis of selected regions (DANSR) uses targeted DNA analysis and digitally analyzes sequencing results from targeted, selected genomic regions on particular chromosomes. This technique is touted as being potentially more efficient than MPSS because it uses fewer genetic fragments.
