Overview of Hemostasis and Thrombosis Pharmacology

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Overview of Hemostasis and Thrombosis Pharmacology

Just as there are natural pathways for clotting, clot breakdown, and clot inhibition, there are also pharmacological therapies that serve these same functions. There are many disorders, both inherited and acquired, that require the use of these drugs for improved morbidity and mortality.
Next, we will discuss the following drug classes:
  1. Anticoagulants: Heparins, warfarin, direct factor Xa iInhibitors, direct thrombin inhibitors
  2. Thrombolytics: Tissue plasminogen activator, streptokinase
  3. Antiplatelet medications: Aspirin and other NSAIDs, GP IIb/IIIa Inhibitors, ADP Inhibitors, PDE/adenosin uptake inhibitors
  4. Coagulation agonists: Factor replacements, vitamin K, antiplasmin
All drug names will be underlined to help you identify them in the following slides. For this presentation, brand names will not be used.